MICR3002 Lecture Notes - Lecture 1: Rolling Circle Replication, Ribosome, Orf Eins
Document Summary
Large variety of variety infect plants: ssrna is the biggest group. Icosahedral shape: seen in 17th century paintings (striped tulips) Transmission of plant viruses: vegetative propogation, flowers, bulbs, seeds, pollen. Internal (embryo) and external (seed coat: pollination (virus internal, wound contamination (virus external, contact, leaf rubbing, root contact, vectors. Insects: nematodes, dodder (cytoplasmic connection between plants and virus transmits the flow, aphids are the largest group of vector transmission. Virus transmission by insects: mode of transmission comes down to virus and insect type, persistent (p&p) Mealybugs: ssrna and dsdna viruses (semi-persistent) Mechanical wounding: all plant viruses are wound parasites, don"t have receptor mechanisms like animal cells. Uncoating of viral genome: co-translational disassembly, particles remove from capsid to form and exit point for the genome, genome binds to ribosome and translates, particle disassociates while translation. Can use 1 or many strategies: needs to do this since eukaryotic cells since only the 1st orf is translated and others are ignored.
