NUTR1023 Lecture Notes - Lecture 1: Omega-3 Fatty Acid, National Health And Medical Research Council, Inuit Diet
Module 1 readings summary !
Tapsel - Chapter 1
Homeostasis - the physiological process by which the internal systems of the body are
maintained at equilibrium, despite variations in external conditions !
Types of research methods !
Mechanistic reaction !
•highly controlled experiments that use cell cultures or animal models!
•Explain how the isolated compounds in food can act on physiological and biochemical
processes.!
•explains natural processes in physical or deterministic terms. !
Observational studies !
•stronger than mechanistic research because they are more directly related to the consumption
of food and measurements of human health !
•less controlled than a laboratory setting !
•It measures something from an existing population !
Randomised controlled trials !
•best evidence for cause and effect relationship !
•Randomly allocating participants into different intervention groups!
•Including a ‘control’ or ‘comparison’ group in order to judge the effects of the intervention #
Levels of evidence !
!
Framingham heart study
-longitudinal study !
-investigate common characteristics that contribute to the development of cardiovascular
disease (CVD) over a long period of time. !
Nutrigenetics !
-how genetic variation affects nutrition absorption, tolerance, requirements etc.!
Nutrigenomics !
-how food and nutrients affect evolution of genome, gene expression etc. !
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Homeostasis - the physiological process by which the internal systems of the body are maintained at equilibrium, despite variations in external conditions. Mechanistic reaction: highly controlled experiments that use cell cultures or animal models, explain how the isolated compounds in food can act on physiological and biochemical processes, explains natural processes in physical or deterministic terms. Observational studies: stronger than mechanistic research because they are more directly related to the consumption of food and measurements of human health, less controlled than a laboratory setting, it measures something from an existing population. Randomised controlled trials: best evidence for cause and e ect relationship, randomly allocating participants into di erent intervention groups, including a control" or comparison" group in order to judge the e ects of the intervention. Investigate common characteristics that contribute to the development of cardiovascular disease (cvd) over a long period of time. How genetic variation a ects nutrition absorption, tolerance, requirements etc.