HUBS1403 Lecture Notes - Lecture 10: Urinary Bladder, Tight Junction, Goblet Cell
18 May 2018
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Lecture'10'–'Epithelia'
!
1. Describe!what!body!tissue!is!and!list!the!four!types!of!tissue!in!the!body.!
• Nervous!tissue!
• Muscle!tissue!
• Epithelial!tissue!
• Connective!tissue!
!
2. Briefly!describe!the!following!junctions!
• Tight!junction!–!formed!from!interlocking!membrane!proteins!fusing!together!adjacent!cells!
• Adherents!junction!–!resists!separation!of!cells!during!contractile!activities;!contains!plaque!
• Desmosomes!–!links!opposing!membranes!and!resists!mechanical!forces;!contains!plaque!
• Hemidesmosomes!–!anchors!epithelial!cells!to!basement!membrane!
• Gap!junction!–!interlocking!membrane!channel!proteins!permit!free!diffusion!of!molecules!from!cell!
to!cell!
!
3. Fill!in!the!table!
Type!of!epithelia!
Description!
Where!it!can!be!found!
Function!
Simple!
squamous!
A!single!layer!of!flat!cells!that!
resembles!a!tiled!floor;!centrally!
located!nucleus!that!is!flattened!
Lines!cardiovascular!
and!lymphatic!system!
Filtration,!diffusion,!
secretion!
Simple!cuboidal!
Single!layer!of!cubeOshaped!cells,!
centrally!located!nucleus!
Covers!surface!of!
ovary,!lines!lens!of!
eye,!lines!kidney!
tubules!
Secretion!and!
absorption!
Nonciliated!
simple!columnar!
A!single!layer!of!nonciliated!
column!like!cells!with!oval!nuclei!
near!base!of!cells!
Lines!gastrointestinal!
tract!
Secretion!and!
absorption!
Ciliated!simple!
columnar!
A!single!layer!of!ciliated!column!
like!cells!with!oval!nuclei!near!
base!of!cells.!Goblet!cells!usually!
interspersed!
Lines!bronchioles,!
fallopian!tubes,!uterus,!
ventricles!of!brain!
Move!mucus!and!foreign!
particles!
Pseudostratified!
columnar!
Appears!to!have!several!layers!as!
nuclei!are!at!various!levels.!Cell!
attached!to!basement!membrane!
in!a!single!layer,!but!some!do!not!
extend!to!apical!surface!
Upper!respiratory!
tract,!lines!larger!
ducts!
Secretes!mucus!
Stratified!
squamous!
Two!or!more!layers!of!cells;!cells!
in!apical!layer!are!squamous,!
deeper!cells!vary!from!cuboidal!
to!columnar!
Superficial!layer!of!
skin,!lines!wet!
surfaces,!covers!
tongue!
Protection!and!defense!
Stratified!
cuboidal!
Two!or!more!layers!of!cube!
shaped!cells!
Ducts!of!sweat!glands!
and!esophageal!
glands;!male!urethra!
Protection,!secretion,!
absorption!
Stratified!
columnar!
Consist!of!shortened,!irregularly!
shaped!cells,!apical!layer!has!
columnar!cells!
Urethra,!excretory!
ducts,!anal!mucous!
membrane!
Protection!and!secretion!
Transitional!
Variable!appearance.!Looks!like!
stratified!cuboidal!epithelium!
except!apical!layer!cells!tend!to!
be!large!and!rounded!
Urinary!bladder,!
ureters!and!urethra!
Allows!urinary!organs!to!
stretch!and!maintain!
protective!lining!
!
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