HUBS1403 Lecture Notes - Lecture 6: Extracellular Fluid, Lipid Bilayer, Cell Membrane
28 Jun 2018
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Lecture 6 – Functional Compartments of the Body: Cells
Name the three major fluid compartments of the human body.
Name the three major fluids and underline that which contributes the greatest amount to total body water volume.
D
Complete definitions for the terms above.
Complete the following table concerning solutes in different body fluid compartments.
Body fluid compartment
Sodium Ions, Na+
Potassium Ions, K+
Chloride Ions, Cl-
Intracellular fluid
Interstitial fluid
Plasma
Name and describe the three main parts of a cell.
What are the two general classes of cells in the body?
What are the three main parts of the cell? Underline the one which is the most varied and complex and name some
of its inclusions.
D
Complete definitions for sex cell, somatic cell, nucleus, cytoplasm and cell membrane.
Describe the structure and function of the plasma membrane.
What is main macromolecule that makes up the bulk of the plasma membrane?
Is the membrane single- or double-layered? Why?
What are the two classes of proteins found in the plasma membrane and how do they differ?
What is a glycocalyx?
Name some functions of the cell membrane.
D
Complete definitions for phospholipid bilayer, integral protein, transmembrane protein, peripheral
protein, glycocalyx, proteoglycan and glycoprotein.
find more resources at oneclass.com
find more resources at oneclass.com
Lecture 6 – Functional Compartments of the Body: Cells
Explain the concept of selective permeability.
Group the following molecules based on how freely they will cross the cell membrane on their own.
Carbon dioxide, CO2 Water, H2O Chloride ions, Cl- Cholesterol Haemoglobin
Oxygen, O2 Hydrogen Ions, H+ DNA Collagen Globular protein
Freely enter
Unable to enter
How will those that are unable to cross the membrane enter the cell? Can these processes be controlled?
D
Complete a definition for selective permeability.
Define the electrochemical gradient and describe its components.
Inside active muscle cells, oxygen is used up in cellular respiration. What will this do to the concentration of oxygen
inside the cell?
Nearby, capillaries carry oxygen-rich blood from the lungs. What will happen to the oxygen in the blood when it
passes by the muscle cell? Why does this occur?
Cells actively pump Na+ ions across the membrane into the extracellular fluid whilst also pumping K+ ions into the
cell. What will happen to the concentration of Na+ inside the cell?
What will happen to the overall charge of the interior of the cell assuming more Na+ is pumped out than K+ in?
When this process is at equilibrium, the potential across the membrane is called what?
When sodium channels open, which way will the Na+ ions travel?
Which two forces are responsible for this?
D
Complete definitions for concentration gradient, electric gradient, resting membrane potential and
electrochemical gradient.
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find more resources at oneclass.com
Lecture 7 – Membrane Dynamics
Describe the passive processes that transport substances across the plasma membrane:
• Simple diffusion
• Facilitated diffusion – channel mediated; carrier mediated
• Osmosis
Select the correct options in the following statement:
͞Molecules generally move from [high/low] concentration to [low/high] concentration.͟
D
Complete a definition for diffusion.
List the five factors that can affect the rate of diffusion.
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2
3
4
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Why can CO2 and O2 cross the cell membrane by simple diffusion but water and Cl- cannot?
What then are the two processes that allow water and Cl- to diffuse across the membrane? Which requires a
conformational change in the membrane protein?
What are three features of carrier-mediated transport?
Do these diffusion processes require energy to function?
D
Complete definitions for simple diffusion, channel-mediated facilitated diffusion, carrier-mediated
facilitated diffusion and passive transport..
Osmosis is the diffusion of which molecule across the selectively permeable cell membrane?
Why does the concentration of solutes govern the direction of osmosis?
D
Complete a definition for osmosis.
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Name the three major fluid compartments of the human body. Name the three major fluids and underline that which contributes the greatest amount to total body water volume. Complete the following table concerning solutes in different body fluid compartments. Name and describe the three main parts of a cell. Underline the one which is the most varied and complex and name some of its inclusions. D complete definitions for sex cell, somatic cell, nucleus, cytoplasm and cell membrane. Describe the structure and function of the plasma membrane. Complete definitions for phospholipid bilayer, integral protein, transmembrane protein, peripheral protein, glycocalyx, proteoglycan and glycoprotein. Lecture 6 functional compartments of the body: cells. Group the following molecules based on how freely they will cross the cell membrane on their own. Carbon dioxide, co2 water, h2o chloride ions, cl- cholesterol haemoglobin. Oxygen, o2 hydrogen ions, h+ dna collagen globular protein. Define the electrochemical gradient and describe its components.
