HUBS1403 Lecture Notes - Lecture 8: Pericentriolar Material, Endoplasmic Reticulum, Spindle Apparatus

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Lecture 8: intracellular compartments: describe the structure and function of cytoplasm, cytosol and organelles (including cytoskeleton, centrosome, cilia and flagella, ribosomes, endoplasmic reticulum, golgi complex, lysosomes, peroxisomes, proteasomes, mitochondria) Cytoplasm: cytoplasm consists of all the cellular contents between the plasma membrane and the nucleus two components: (1) the cytosol and (2) organelles. Increase surface area of the cell for microvilli (finger like projections if plasma membrane) If cell has no centrosome = not capable of cell division: overall function: pericentriolar material contains tubulines that build microtubules 2. The outer surface of rough er is studded with ribosomes, the sites of protein synthesis. Proteins made here enter the er for processing and sorting. Golgi: most of the proteins synthesized by ribosomes attached to rough er are ultimately transported to other regions of the cell. Carry out autophagy, the digestion of worn-out organelles. Implement autolysis, the digestion of an entire cell.

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