HUBS1403 Lecture Notes - Lecture 19: Adenylyl Cyclase, Thyroid, Pineal Gland

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In addition several organs not classified as glands secrete hormones hypothalamus, thymus, pancreas, ovaries, testes, kidneys, stomach, liver, small intestine, skin, heart, adipose, placenta: endocrine glands + System: the science of the structure and function of the endocrine glands and the diagnosis and treatment of disorders of the endocrine system is endocrinology. See animation: chemically, hormones can be divided into two broad classes: those that are soluble in lipids, and those that are soluble in water. Lipid-insoluble hormones cannot pass through the plasma membrane they only interact with surface. = testes, estrogen, progesterone = ovaries thyroid hormones: t3 t4 = thyroid gland: nitric oxide: endothelial cells lining blood vessels. Most water soluble hormone molecules circulate in the watery blood plasma in a free form, but most lipid soluble are bound to transport molecules transport molecules synthesised in the liver. The activated receptor- hormone complex then alters gene expression: turns on specific genes of the nuclear dna on or off.

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