HUBS1403 Lecture Notes - Lecture 23: Extracellular Fluid, Skeletal Muscle, Resting Potential

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^ critical determinant of transmembrane ion movements (thus ion. Also, positively charged cations move toward a negatively charged area, and negatively charged anions move toward a positively charged area (the electrical aspect of the gradient) As ions move, they create a flow of electrical current that can change the membrane potential. Leak channels are found in nearly all cells, including the dendrites, cell bodies, and axons of all types of neurons. Mechanically gated channel opens or closes in response to mechanical stimulation in the form of vibration, touch, pressure or tissue stretching: the force distorts the channel from its resting position opening the gate, eg. Auditory receptors in the ear, and touch receptors / pressure receptors in skin. Voltage gated channel: opens in response to a change in membrane potential (voltage) Lauren hunt: concentration gradients of some ions are maintained by carrier proteins (e. g. the na/k pump, the atp driven, na/k exchange pump establishes.

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