HUBS1404 Lecture Notes - Lecture 30: Penicillium Chrysogenum, Papaver Somniferum, Ibuprofen Brand Names
19 Jul 2018
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Document Summary
Study of the effects of chemical substances (eg drugs) on the function of biological systems. Includes the study of the effects of endogenous substances (ie those produced within the body) including hormones and neurotransmitters. Show at a molecular level how drubs work: discover new drugs or new uses of currently known drugs. Identify new and potential drug targets for the treatment of specific disease states and disorders: develop testing procedures to measure the effectiveness of drugs and their adverse effects. Broadly defined as any chemical substance that affects biological organisms and processes. Drug nomenclature: drugs have 3 difference names: name. Natural products: plant and herb extracts: 5000bc sumerians used opium poppies (papaver somniferum) - we now have morphine, ~300bc hippocrates used the bark of the weeping willow tree to treat headaches - aspirin. 1928: penicillin - prototypic -lactam antibiotic, isolated from penicillium notatum. Chemical modifications and synthesis: modify natural hormones (eg prednisolone synthetic steroid)
