BIOL103 Lecture Notes - Lecture 7: Cell Division, Somatic Cell, Cell Growth

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Overview: cell division results in genetically identical daughter cells and plays an important role in growth, development and tissue repair. Understand that division of eukaryotic cells is a highly regulated process that requires dna replication and equal distribution of dna: exact amount of chromosomes in daughter cells needed. M phase: g1, g2, learn phases . In animal cells, assembly of spindle microtubules begins in the centrosome: also called the microtubule organising centre. Microtubule asters form (a radical array of short microtubules) extends from each centrosome. Centrosomes begin to move to opposite poles: prometaphase. Chromosomes start to move as microtubules bind to kinetochores present within chromosomes. Microtubules start to form the mitotic spindle: metaphase. Chromosomes line up along the equatorial plane of the cell. Forming the metaphase plate: anaphase, telophase. Sister chromatids separate at their centromeres to form single chromosomes. Microtubules shortedn and pull chromosomes to opposite poles (cid:894)look like v"s(cid:895) Nuclear envelope forms, surrounding each group of chromosomes.

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