MEDI110 Lecture Notes - Lecture 10: Cardiac Muscle, Blood Pressure, Hypertrophy

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Increase in pns activity and reduction in ssns discharge, and s-a node firing rate. Increase in cardiac hypertrophy increases the heart size. Stop in training causes heart to return to pre-training size. adaptation) (sites of cardiovascular. How vo2 max can show the change due to sustained endurance activity. Vo2 max = hrmax x svmax, x (a-v)o2max. A-vo2 = difference between muscle blood flow and capillaries mitochondria. Increase in the quantity of oxygen is extracted due to: Elevation of oxygen content and a decrease in mixed venous oxygen content. For example a study done on students for 55 days with training, extraction increases from 15-17 ml per 100 ml which is a 13% increase. Increase in heart mass and volume with long term training. Increase of lvedv (left ventricular, end diastolic volume) during training and when at rest. Migration of fibres to a higher oxidative capacity. Increase size of left ventricular wall due to volume overload.

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