MEDI213 Lecture Notes - Lecture 3: Respiratory Acidosis, Metabolic Acidosis, Carbonic Acid

• School: UOW
• Department: Medical and Health Sciences
• Course: MEDI213
• Professor: Karen Walton

Document Summary

Acid base balance: key organs = lungs and kidney, how do they maintain homeostasis, icf + ecf buffers (hco3, h2co3) 1st line of defence, lungs: alveolar ventilation which controls paco2 (thus improving efficiency of. Hco3, h2co3, h2co3 biffers: kidneys: excretion h+ which controls hco3 (slow) Normal acid base balance: the conc. of h2co3 is determined by lungs and their respiratory capacity, the conc. of volatile acids is determined by the kidneys and the amount fo buffers produced e. g. hco3, h+ excreted. E(cid:454)a(cid:373)ple of (cid:271)od(cid:455)(cid:859)s (cid:272)orre(cid:272)tio(cid:374: e. g. too much acid, lu(cid:374)gs dete(cid:272)t rise i(cid:374) h(cid:1006)co(cid:1007), h+ a(cid:374)d lu(cid:374)gs i(cid:374)(cid:272)rease to (cid:858)(cid:271)low off(cid:859) co(cid:1006, kidneys excrete acidic urine and reabsorb bicarbonate, recovered, = compensation. Too low bicarb = metabolic acidosis (normal co2 but normal bicarb) caused by kidney (red arrow) Low ph but co2 = respiratory acidosis lu(cid:374)gs are(cid:374)(cid:859)t (cid:272)o(cid:373)pe(cid:374)sati(cid:374)g as the(cid:455) (cid:374)or(cid:373)all(cid:455) should (blue arrow)