BIOL1007 Lecture Notes - Lecture 11: Flavin Adenine Dinucleotide, Nicotinamide Adenine Dinucleotide, Electrochemical Gradient
19 May 2018
School
Department
Course
Professor
Describe how cellular respiration transfers electrons from glucose to
oxygen through a range of intermediate chemicals which release
their
energy by breaking bonds to the electron transport chain
Strategy of fuel oxidation
Stage 1
Rip Hs/electrons (H/e-) out of fuels
-
Fuels break up into 2 carbon units
-
Red = pathways, groups of enzymes which do stripping of h and e-s
-
Screen clipping taken: 29/09/2017 9:45 PM
Stage 2
Rip H/e- out of acetate
-
Complete oxidation of carbon atoms to CO2
-
Cs become fully oxidised
-
Screen clipping taken: 29/09/2017 9:46 PM
Note…
H/e- strippers are carriers as well
-
Nicotinamide adenine dinucleotide (NAD)
-
L11 - respiration in animals
Friday, 29 September 2017
9:42 PM
Mod 2 Energy Systems and Cells Page 1
Love to oxidise CH2-CHOH
•
Becomes NADH
•
Nicotinamide adenine dinucleotide (NAD)
-
Love to oxidise -CH2-CH2- to -CH=CH-
•
Becomes FADH2
•
Flavin adenine dinucleotide (FAD)
-
Once you rip something out, you carry it, so CANNOT do anymore ripping
-
Both are in limited supply
-
Screen clipping taken: 29/09/2017 9:48 PM
Phase 3
Capturing energy of the H/e-
-
Reaction between H and O liberates lots of energy
-
Want to capture as chemical/potential energy
-
Formation of the proton gradient ie. A battery
-
Causes difference in proton conc across membrane
•
Energy stored in proton gradient
•
H/es passed to carriers in inner mitochondrial membrane, causes protons to be
pumped from matrix (inside) to cytoplasm
-
Screen clipping taken: 29/09/2017 9:49 PM
Describe the components of cellular respiration including glycolysis,
formation of Acetyl coenzyme A, citric or TCA cycle and electron
transport chain and the production of ATP
Protons flow through the channel in inner mitochondrial membrane
-
This then interacts with the subunits of the ATP synthase (finger in mandarin)
○
Generates ATP from ADP and phosphate
○
As they flow through, they cause another protein to rotate
-
ATP goes to cytoplasm to do work (energy currency of life)
-
Making ATP with H+ gradient
Mod 2 Energy Systems and Cells Page 2
Document Summary
Describe how cellular respiration transfers electrons from glucose to oxygen through a range of intermediate chemicals which release their energy by breaking bonds to the electron transport chain. Red = pathways, groups of enzymes which do stripping of h and e-s. Mod 2 energy systems and cells page 1. Once you rip something out, you carry it, so cannot do anymore ripping. Reaction between h and o liberates lots of energy. Formation of the proton gradient ie. a battery. H/es passed to carriers in inner mitochondrial membrane, causes protons to be pumped from matrix (inside) to cytoplasm. Describe the components of cellular respiration including glycolysis, formation of acetyl coenzyme a, citric or tca cycle and electron transport chain and the production of atp. Protons flow through the channel in inner mitochondrial membrane. As they flow through, they cause another protein to rotate. This then interacts with the subunits of the atp synthase (finger in mandarin)
