EXSS2022 Lecture Notes - Lecture 9: Troponin, Vo2 Max, Myocyte
22 Aug 2018
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Impact of fatigue: measuring fatigue: difficult, animals (isolate muscle fibre, whole muscle in-vitro, or anesthesia in-situ, humans (in-vivo muscle tests, or muscle biopsies) Age vo2max young adult endurance-trained: 20-30 65 ml. kg-1. min-1 young adult sedentary: 20-30 45 ml. kg-1. min-1 aged healthy sedentary: 65-70 25 ml. kg-1. min-1 aged copd sedentary: 65-70 15 ml. kg-1. min-1. Major problems occur when power output to do. Fatigue challenges: etiology (causes) of fatigue, status of individual (age, fitness, gender, diet, sleep, stress, disease diet, hydration, task required of individual (intensity, mode, duration, environment (altitude, heat, cold) Fatigue: lecture 9: factors affecting fatigue, hard to study fatigue as different activities produce different decreases in power (result of different mechanisms, great difficulty in isolating mechanisms for the inability to sustain performance. Types of fatigue: central (motivation, mc, spc, mn, peripheral (peripheral nerve, nmj, membrane, t-tubule, ca+ from sr, ca+ to troponin, cross-bridge cycle) Failure of force generation of the whole muscle: The failure, whether voluntary or involuntary of neural drive, resulting in:
