EXSS3037 Lecture Notes - Lecture 21: Digestion, Lactoferrin, Phagosome

• School: University of Sydney
• Department: Exercise and Sport Science
• Course: EXSS3037
• Professor: Rhonda Orr

Document Summary

Why: antigen: molecules initiating the production of antibodies (antibody generator); evoking a response by cells of the immune system. Immune system: protects you & allows you to regain function. 2: lymph nodes: antigens from skin & tissues, spleen: antigens from blood, mucosa associated lymphoid tissue (malt): antigens from respiratory & gi tract (cid:523)e. g. tonsils, adenoids, peyer(cid:495)s patch(cid:524) 4: 2nd line of defense non-specific/innate, fever, protective proteins (cytokines, phagocytosis, nk cells, inflammation, complement, 3rd line of defense specific/acquired, cell-mediated, humoral. Innate (specific) immunity first barrier: skin, mechanical barrier, endogenous flora, low ph (3-5, mucosa, mechanical barrier, endogenous flora, antimicrobial proteins in mucous. Phagocytosis: (cid:498)the killers(cid:499, neutrophil: phagocytosis & activation of bacterial mechanisms (low neutrophils = immune suppression & increased illness, monocyte/macrophage: phagocytosis & antigen presentation. 8: above figure, 3rd line of defense = antigen-presenting cells, antigen-presenting is necessary for both pathways, (cid:884) p/w(cid:495)s, cell-mediated, humoral, cells must touch each other for recognition to occur.