EXSS3050 Lecture Notes - Lecture 7: Glycated Hemoglobin, Myopathy, Claudication
Document Summary
Rationale for use of prt in treatment of t2d: Muscle characteristics in t2dm: weakness, decreased glycogen storage & atrophy compared to age-matched peers, potential causes, genetic/epigenetic profile, neuropathy, diminished vascular supply, primary myopathy, increased cortisol and cytokines/decreased igf-1 associated with visceral obesity, statin usage. Morbidities: lecture 6b: study below: high intensity rt + diet in older adults with t2d effect on glycosylated. Hb: weight lifters who have increased fat in muscle = have worse hba1c not bad for those who do aerobic pa, so use rt & aerobic exercise, greater benefit with rt. Frequency: maximum 72 hours between sessions, every 48 hours optimal, greater reduction in day 1 postprandial glucose and insulin after 60 min mod intensity aerobic session [compared to 30min mod intensity aerobic session, same reduction in overall hyperglycemia. Insulin sensitivity wears off between 48-72hrs, so exercise is critical now, aim to do it daily. Exercise dose recommendations in older adults with t2d: