300884 Lecture Notes - Lecture 2: Adverse Drug Reaction, Clinical Pharmacology, Pharmacodynamics
Document Summary
A branch of medicine which deals with drug action on a biological system. Drugs: all drugs are chemicals but not all chemicals are drugs. Formulation: how the drug is administered; tablet, injection etc. All medicines are drugs but not all drugs are medicines. Pharmacotherapeutics: drugs in the prevention or treatment of diseases. Indication- an illness or disorder for which a drug has documented usefulness. Contraindication- a factor that increases the risk in using a drug. Absolute c: drug should not be given at all. Adverse drug reaction: an undesirable reaction to a drug. Areas studies: pharmacokinetics: absorption (orally), distribution (to the whole body), metabolism (breaking down of drug/molecule (liver plays a crucial role in metabolism) and elimination (eliminated from the body via renal excretion) ; concentration in blood: orally, g. i tract, absorbed in blood. ; concentration at site of action: relieving pain via mechanism. Pharmacokinetics: what the body does to the drugs (a. d. m. e)