PHAR2210 Lecture Notes - Lecture 17: Stereocenter, Chemical Formula, Stereoisomerism
Document Summary
Isomers are compounds with the same molecular formula but different structural formulas or spatial arrangements: structural isomers: Share the same molecular formula (e. g. below = C7h8o) and molecular mass (108 g/mol: but since atoms are linked differently they are very distinct molecules, spatial isomers (stereoisomers) Same chemical properties except when interacting with chiral systems. Chiral centre : a carbon atom within a drug or other molecule to which are attached 4 different atoms or groups of atoms, also called an asymmetrical centre. Stereoisomers two molecules containing a chiral centre that are identical in atomic composition yet differ in the 3- dimensional positions of the atoms. Such molecules are usually mirror images and non-superimposable: also often known as enantiomers, e. g. your hands are non-superimposable mirror images. Optical activity the ability of pure solutions of an enantiomer or stereoisomer to rotate polarised light.
