EHR523 Lecture Notes - Lecture 12: Lymph Node, Adaptive Immune System, Bone Marrow

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Introduction: lymphoma: refers to the malignant growth of lymphocytes (white blood cells), sixth most common cancer diagnosed in men and women accounting for ~5% of all cancer diagnoses in. Median age of ~40 yrs at diagnosis. In 2017, lymphoma was the 11th most common cause of cancer death in both sexes (1 death every 6 hrs): lifetime risk for developing lymphoma is 1:30 in men and 1:45 in women. Anatomy of the lymphatic system: consists lymph nodes and vessels that contain lymph fluid that run throughout the body, functions as the body"s sewer system" by: Manages fluid levels in our body tissues by removing all fluids that leak out of our blood vessels. Plays an important role in general and specific immune responses: fighting bacteria and other infections, destroying old or abnormal cells, such as cancer cells, two (2) main types of lymphoid tissues: Central lymphoid tissues: produce lymphocytes from immature cells.

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