GMED1000 Lecture Notes - Lecture 9: Antiviral Drug, Viral Envelope, Serology
Document Summary
Very small, can only been seen with an electron microscope. Cant reproduce independently, can only replicate using a host cells metabolism. A virus that infects a bacteria is called a bacteriophage. Class 4: single stranded rna (ss rna), positive sense. Class 5: single stranded rna (ss rna), negative sense. Class 6: ss rna positive sense, with ds dna intermediate before replication (aka retroviruses) Class 7: ds dna with positive sense, part ss dna, with ss rna intermediate (reversiviruses) + and - sense (used in baltimore scheme classification) One strands codes for something, the other is just the opposite. + strand is the coding one, - is the non-coding. Therefore + rna can be used to create proteins immediately. A - strand must go to a nucleus, get the + coded and then can create proteins using that. Most human infections caused by icosahedral or helical. Can be used to type bacteria and possibly as an antibiotic alternative.