GMED2000 Lecture Notes - Lecture 4: Regulatory T Cell, Natural Killer Cell, Kupffer Cell
17 Jul 2018
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Document Summary
Body is continually threatened by foreign substances, infectious agents and abnormal cells. Immune system = body"s major defence mechanism. The immune system defends and protects the body from infection; removes and destroys damaged or dead cells and identifies and destroys malignant cells. Immune system is activated from a small laceration to a systemic infection. The lymphatic system is responsible for the highly specific immune response. Thymic hormone, thymosin, are thought to aid in maturation of prothymocytes which develop into t lymphocytes. Acts as a storage for blood and processes expired rbcs and platelets. Intercepts foreign substances that enter the body by respiratory means. Foreign substances are engulfed by macrophages or lymphocytes activate an immune response. Produces and stores stem cells from which all components of blood are derived from. Circulation, body tissue, liver (kupffer cells) alveoli, spleen, tonsils, lymph nodes, bone marrow, brain. Trap and phagocytose foreign substances and cellular debris. Secretion of interleukin-1 to stimulate lymphocyte growth.
