HBS109 Lecture Notes - Lecture 5: Mammary Gland, Homeostasis, Vasopressin

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25 Jul 2018

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Steroid hormones: describe how steroid hormones are transported in the blood and how they interact with their target cell. Attached to a carrier protein; cell membrane receptor. Attached to a carrier protein; intra-cellular receptor. Dissolved in plasma; cell membrane receptor: list the endocrine structures that are directly influenced by the hypothalamus. Between the stomach and the small intestine. On the superior border of each kidney. On the anterior surface of the trachea. Basal metabolism rate and calcium ion regulation. Sodium retention, water balance and bone and muscle growth.

Related Questions

Which of the following is notone of the effects of muscle-building anabolic steroids?

A.	Cessation of menstrual periods in women
B.	Increased body and facial hair in women
C.	Reduced risk of cancer and heart disease in men
D.	Breast tissue diminution in women
E.	Kidney disease

Which of the following statementsabout hormones is true?

A.	The same hormone can cause different responses in differenttypes of cells.
B.	Whenever a hormone encounters a cell with a unbound receptor towhich it can bind, it can bind.
C.	The receptor for a hormone may be on the secreting cellitself.
D.	The receptor for a hormone may be in the plasma membrane orinside the cell.
E.	All of the above

Which of Wigglesworth's observationsof Rhodnius bugs helped explain the role of insecthormones?

A.	A blood meal triggers molting in these bugs.
B.	If decapitated immediately following a blood meal, the bug willmolt.
C.	When two bugs are connected, they molt simultaneously.
D.	When two bugs are connected, the feeding status of one cantrigger molting in the other.
E.	When two bugs are decapitated and connected, they do not moltinto adults.

Steroid hormones

A.	must bind to carrier proteins to be transported in the blood totheir target cells.
B.	bind with receptor proteins in the plasma membrane.
C.	are synthesized from epinephrine in the adrenal gland.
D.	are released from the cells that make them by exocytosis.
E.	are mostly derivatives of the amino acid tyrosine.

Which of the following is notone of the distinct chemical groups to which hormones belong?

A.	Steroids
B.	Proteins
C.	Peptides
D.	Carbohydrates
E.	Amines

Which of the following hormones isnot paired correctly with its target organ?

Oxytocin

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QUESTION 1

Which of the following is an example of an extracellular signal molecule?

	a.	IP₃
	b.	cAMP
	c.	Insulin
	d.	Diacylglycerol

2 points

QUESTION 2

Nuclear hormone receptors _____

	a.	Bind to water soluble ligands
	b.	Activate second messengers
	c.	Regulate transcription in response to ligand binding
	d.	Are normally located on the plasma membrane

2 points

QUESTION 3

Which of the following does not occur when a receptor tyrosine kinase is bound by ligand?

	a.	Phosphorylation of the RTK
	b.	Cytoplasmic proteins bind the phosphorylated RTK
	c.	Dimerization of the RTK
	d.	The RTK binds to DNA to regulate transcription

2 points

QUESTION 4

Which of these is a logical signal-transduction pathway?

	a.	An intracellular receptor activates phospholipase C, which cleaves a membrane protein to form IP₃, which then activates the opening of an ER channel protein, which releases cyclic AMP into the cytoplasm, where it binds to an intracellular enzyme that carries out a response.
	b.	A G-protein-linked receptor activates G protein, which activates phospholipase C, which cleaves a membrane lipid to form IP₃, which binds to a calcium channel on the ER, which opens to release calcium ions into the cytoplasm, which bind to an intracellular enzyme that carries out a response.
	c.	An ion-channel receptor opens, allowing a steroid hormone to enter the cell; the steroid hormone then activates protein kinases that convert GTP to GDP, which binds to an intracellular enzyme that carries out a response.
	d.	A tyrosine-kinase receptor activates adenylyl cyclase, which activates phospholipase C, which converts ATP into cyclic AMP, which binds to an intracellular enzyme that carries out a response.

2 points

QUESTION 5

Which of the following is an example of signal amplification?

	a.	activation of an enzyme molecule
	b.	activation of a specific gene by a growth factor
	c.	Breakdown of many cAMP molecules
	d.	activation of 100 molecules by a single signal binding event

2 points

QUESTION 6

Consider a signal transduction pathway that utilizes cAMP as a second messenger to activate PKA (Protein Kinase A). Which of the following situations will result in the cellular response?

		The G protein releases GDP and binds to GTP
		The target protein (adenylyl cyclase) is inactive
		The regulatory subunits of PKA (Protein Kinase A) are bound to the catalytic subunits
		The appropriate G protein is bound to GDP

2 points

QUESTION 7

Which of the following is found in only some signal transduction pathways? [In other words, which is not found in all signal transduction pathways?]

		Receptor protein
		Extracellular signal molecule
		Intracellular signaling molecule
		Cellular response
		Effector protein

2 points

QUESTION 8

The enzyme that specifically catalyzes the conversion of ATP to cAMP is:

		Adenylyl phosphatase
		Adenylyl kinase
		Adenylyl dehydrogenase
		Adenylyl cyclase

2 points

QUESTION 9

If an animal cell suddenly lost the ability to produce GTP, what might happen to its signaling system?

		It would use ATP instead of GTP to activate and inactivate the G protein on the cytoplasmic side of the plasma membrane.
		It would not be able to activate and inactivate the G protein on the cytoplasmic side of the plasma membrane.
		It would employ a transduction pathway directly from an external messenger.
		It would be able to carry out reception and transduction but would not be able to respond to a signal.

2 points

QUESTION 10

A hormone signal is sent from the brain to other parts of the body via the bloodstream. Why do only certain cells respond to this signal?

		Hormones do not last long enough in the bloodstream to stimulate a cellular response
		Only cells that have a specific transcription factor gene will be able to respond to the signal
		Only cells in the immediate vicinity of the cell sending the signal will respond
		Only cells that have a receptor for the specific signal will be able to respond to it

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HBS109 Lecture Notes - Lecture 5: Mammary Gland, Homeostasis, Vasopressin

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