MFAC1521 Lecture Notes - Lecture 53: Pulmonary Hypertension, Hypoglycemia, Vasopressin
8 Jul 2018
School
Department
Course
Professor
Document Summary
*total blood volume of a newborn = 300 ml. Cardiological changes at birth: removal of placental circulation (closure of umbilical artery) In the fetal circulation, the placenta receives 50% of combined cardiac output. Stretch: closure of umbilical vein and ductus venosus (dv) Within 3 hours after term birth, smooth muscle of dv constricts to shut off the shunt that bypasses the liver: increase in pulmonary blood flow. During fetal life, pulmonary vasculature resistance is high and thus lungs only get 7% of cco. Pulmonary vasculature dilates due to: reduction in lung expansion. In uterus, lungs are filled more with liquids as it takes up more space than air. *the white bars represents normal lung volume whereas the black bars represents reduced lung volume where 60% of lung liquid has been taken. The results shown are for pulmonary vascular resistance and pulmonary blood flow.
