BIOS1167 Lecture Notes - Lecture 7: Thyroid, Natriuretic Peptide, Pancreatic Islets

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Consists of cns (brain, spinal cord), and pns (peripheral nerves around body) Message sent via electrical impulse = action potential. The hormones are transported via the blood to the cell target. Consists of hypothalamus, pituitary gland, thyroid, adrenal gland, heart, kidney, adipose tissue, gonad, pancreatic islets, pineal glands. Cells located in specialised endocrine tissue (in many body organs, tissues) Hormones circulate freely or are bound to proteins in the plasma. Classified by chemical structure = amino acid derivatives (small molecules - amino group, phosphate group), peptide hormones (insulin - 51 amino acids), lipid derivatives (testosterone, estrogen, sex hormones diffuse across lipid membrane into cell) Protein hormones bind to outside of membrane. Secretin from duodenum in digestive tract targets pancreas/liver to stimulate secretions. Atrial natriuretic peptide from the heart targets the kidney inhibits na+ reabsorption. Erythropoietin from kidney targets bone marrow to stimulate rbc production. Leptin in adipose tissue targets the brain reduces appetite, increases energy expenditure.

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