MBLG2972 Lecture Notes - Lecture 11: Quantitative Genetics, Heritability, Phenotype

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5 Jul 2018

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MBLG2072

Genetics and Genomics

Monica Zanuttini !

460381099

Lecture 11 "Quantitative and quantitative genetics

Qualitative traits: !

Controlled by a few genes of large eﬀect.!

Phenotype can be determined by simple crossing experiments (e.g. attached/detached earlobes).!

Quantitative traits: !

Controlled by many genes and alleles of small eﬀect. !

Environmental factors likely to contribute to phenotype (e.g. IQ in humans). !

Biometrical genetics:!

Partitioning phenotypic variance:"" " " Breeders equation: !

Narrow heritabilities: !

0 = all due to environment """"" Twin coordinance: !

1 = all due to genes!

High heritability = low genetic variability, characteristics

unimportant to natural selection.!

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