PHAR3819 Lecture Notes - Lecture 4: Indigestion, Peptic Ulcer, Esophagogastroduodenoscopy

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Functional gastroduodenal disorder: has a prevalence rate ~20% of the general population. Rome iii - diagnostic criteria for functional dyspepsia. No evidence of structural disease (including at upper endoscopy) that is likely to explain the symptoms. The criteria have to be fulfilled for the last 3 months with symptom onset at least 6 months before diagnosis. An alarm sign is considered to be any sign that raises suspicion of an organic disease. No difference in the incidence of alarm signs has been reported between organic diseases and fd. Bloody or black stools: unintentional or unexplained weight loss, dysphagia (especially in elderly, use of nsaid, use of low dose aspirin. A diagnosis of fd is excluded if the patient is using nsaids or low-dose aspirin and the symptoms are reduced or eliminated when that use is discontinued. Impaired gastric accommodation: delayed gastric emptying, hypersensitivity. Psychological factors (anxiety or history of abuse: history of infectious colitis.

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