PCOL2605 Lecture Notes - Lecture 1: United States Pharmacopeia, Bioavailability, Mannitol
23 Oct 2018
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Tablets are solid preparations containing a single dose of one or more active substances and usually obtained by compressing uniform volume of particles. Everything is more stable in solid state because of confined in crystal lattice proper orientation. Not 100% bioavailable guarantee, first pass (cid:373)eta(cid:271)olis(cid:373), o(cid:374)set of a(cid:272)tio(cid:374) is(cid:374)"t as fast as iv or inhalation. Drug types; protein drugs would be degraded by digestive enzymes. Therapeutics goods order no. 78: standard for tablets and capsules, published 2008, largely follow the. There could be some differences as the latest bp is in 2018. Listed (lower risk) and registered (higher risk) medicines. A tablet must comply with the individual monograph of the bp for a tablet of that type. There are some departures from strict compliance with the bp monograph: For a listed tablet, compliance with the uniformity of dosage units requirements in an individual. Bp (cid:373)o(cid:374)og(cid:396)aph is (cid:396)epla(cid:272)ed with (cid:272)o(cid:373)plia(cid:374)(cid:272)e with the bp"s (cid:396)e(cid:395)ui(cid:396)e(cid:373)e(cid:374)ts fo(cid:396) u(cid:374)ifo(cid:396)(cid:373)ity of weight (mass)
