PHYL2001 Lecture Notes - Lecture 1: Frostbite, Semen Analysis, Internal Intercostal Muscles
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Physiology of Human Body
Systems
PHYL2001
Alyssa Santarelli
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Table of Contents
PHYSIOLOGICAL CONTROL SYSTEMS ........................................................................................ 4
THE NERVOUS SYSTEM ................................................................................................................................... 4
THE AUTONOMIC NERVOUS SYSTEM ............................................................................................................ 4
Anatomy of an Autonomic Neuron ......................................................................................................... 4
Divisions of the Autonomic Nervous System ...................................................................................... 4
Autonomic Conflict ........................................................................................................................................ 6
Autonomic Neurotransmitters ................................................................................................................. 6
PHARMACOLOGY OF THE AUTONOMIC NERVOUS SYSTEM ........................................................................ 7
Noradrenaline Receptors ............................................................................................................................ 7
Acetylcholine Receptors .............................................................................................................................. 8
THE ENDOCRINE SYSTEM ............................................................................................................................... 8
Endocrine Glands ............................................................................................................................................ 9
Hormones ........................................................................................................................................................... 9
The Pituitary Glands ................................................................................................................................... 10
CARDIOVASCULAR PHYSIOLOGY ..............................................................................................12
BLOOD ............................................................................................................................................................. 12
CELLS OF THE BLOOD ................................................................................................................................... 12
THE CARDIOVASCULAR SYSTEM ................................................................................................................. 14
CARDIAC OUTPUT.......................................................................................................................................... 15
FLOW ............................................................................................................................................................... 16
ELECTRICAL CONDUCTIVITY OF THE HEART ............................................................................................ 16
THE ECG ......................................................................................................................................................... 17
HEART VALVES .............................................................................................................................................. 18
BLOOD VESSELS ............................................................................................................................................. 18
RESISTANCE TO FLOW .................................................................................................................................. 19
MEAN ARTERIAL PRESSURE ........................................................................................................................ 19
CAPACITANCE ................................................................................................................................................ 20
VASO-CONSTRICTION AND VENO-CONSTRICTION .................................................................................. 20
MICROCIRCULATION ..................................................................................................................................... 20
CHANGES IN FILTRATION AND ABSORPTION ............................................................................................ 22
CONTROL OF BLOOD FLOW ......................................................................................................................... 22
METABOLIC MEDIATORS ............................................................................................................................. 23
CONTROL OF SYSTEMIC ARTERIAL PRESSURE ......................................................................................... 23
CONTROL OF BLOOD VESSELS ..................................................................................................................... 23
CONTROL OF BLOOD PRESSURE.................................................................................................................. 24
CONTROL OF BLOOD VOLUME..................................................................................................................... 25
AUTOREGULATION OF BLOOD FLOW ......................................................................................................... 25
BLOOD FLOW THROUGH SKELETAL MUSCLE ........................................................................................... 25
CORONARY BLOOD FLOW ............................................................................................................................ 26
ARTHEROSCLEROSIS ..................................................................................................................................... 26
CEREBRAL BLOOD FLOW ............................................................................................................................. 26
SKIN BLOOD FLOW ....................................................................................................................................... 26
RESPIRATORY PHYSIOLOGY .......................................................................................................27
ANATOMY OF THE RESPIRATORY SYSTEM: ............................................................................................... 27
FUNCTION OF THE RESPIRATORY SYSTEM: .............................................................................................. 29
RESPIRATORY PRESSURES: .......................................................................................................................... 29
RESPIRATORY CYCLE: ................................................................................................................................... 29
SPIROMETRY: ................................................................................................................................................. 31
VENTILATION: ................................................................................................................................................ 32
LUNG COMPLIANCE: ...................................................................................................................................... 32
AIRWAY RESISTANCE (RAW): ...................................................................................................................... 33
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MUSCULAR EFFORT: ..................................................................................................................................... 33
COMPOSITION AND PARTIAL PRESSURES OF AIR: ................................................................................... 34
DIFFUSION CAPACITY: .................................................................................................................................. 35
ALVEOLAR GAS EXCHANGE: ........................................................................................................................ 35
Alveolar Gas Equation: .............................................................................................................................. 36
TRANSPORT OF GASES: ................................................................................................................................ 36
Hb-O2 Dissociation Curve: ......................................................................................................................... 37
CONTROL OF VENTILATION: ........................................................................................................................ 37
RENAL PHYSIOLOGY ......................................................................................................................39
BODY FLUID COMPOSITION: ........................................................................................................................ 39
ANATOMY OF THE URINARY SYSTEM: ....................................................................................................... 39
FUNCTION OF THE URINARY SYSTEM: ....................................................................................................... 39
THE NEPHRON: .............................................................................................................................................. 40
GLOMERULAR FILTRATION: ........................................................................................................................ 41
Forces Affecting Glomerular Filtration: ............................................................................................. 41
Glomerular Filtration Rate: ..................................................................................................................... 41
Control of Glomerular Filtration Rate: ............................................................................................... 42
TUBULAR REABSORPTION: .......................................................................................................................... 42
Sodium Reabsorption: ................................................................................................................................ 43
Glucose, Amino Acid, and other Nutrient Reabsorption: ........................................................... 43
Chloride Reabsorption: .............................................................................................................................. 43
WATER REABSORPTION: ............................................................................................................................. 43
Hormonal Control of Water Reabsorption: ...................................................................................... 43
Control of Salt Loss: ..................................................................................................................................... 44
TUBULAR SECRETION: .................................................................................................................................. 44
Potassium Secretion: ................................................................................................................................... 45
Acid/Base Balance: ...................................................................................................................................... 45
Hydrogen Secretion: .................................................................................................................................... 45
URINE EXCRETION: ....................................................................................................................................... 45
REPRODUCTIVE PHYSIOLOGY....................................................................................................46
SEXUAL DIFFERENTIATION: ........................................................................................................................ 46
NEUROENDOCRINE CONTROL OF REPRODUCTIVE FUNCTION:.............................................................. 47
HORMONAL CONTROL OF REPRODUCTION IN MALES: ........................................................................... 47
Spermatogenesis: ......................................................................................................................................... 48
Endocrine Control of Spermatogenesis: ............................................................................................. 49
Foreign Factors Affecting Reproduction in Males: ....................................................................... 50
HORMONAL CONTROL OF REPRODUCTION IN FEMALES: ....................................................................... 50
Ovarian and Menstrual Cycles: .............................................................................................................. 51
Endocrine Control of the Ovarian Cycle:............................................................................................ 52
Endocrine Control of the Menstrual Cycle: ....................................................................................... 53
Fertilization vs no Fertilization: ............................................................................................................ 54
GASTROINTESTINAL PHYSIOLOGY ..........................................................................................54
FUNCTIONS OF THE GASTROINTESTINAL SYSTEM:.................................................................................. 54
NERVES AND HORMONES: ........................................................................................................................... 54
PHASES OF DIGESTION: ................................................................................................................................ 55
ORGANS OF THE GASTROINTESTINAL SYSTEM: ....................................................................................... 55
PRODUCTION AND RELEASE OF GASTRIC ACID: ....................................................................................... 56
CONTROL OF GASTRIC EMPTYING: ............................................................................................................. 57
HORMONAL CONTROL OF THE INTESTINAL PHASE: ............................................................................... 57
CCK RELEASE AND EFFECTS ON PANCREAS: ........................................................................................... 58
THE BILIARY SYSTEM: .................................................................................................................................. 59
INTESTINAL ABSORPTION: .......................................................................................................................... 59
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Document Summary
Divisions of the autonomic nervous system 4. Pharmacology of the autonomic nervous system 7. Composition and partial pressures of air: 34. Glucose, amino acid, and other nutrient reabsorption: 43. Hormonal control of reproduction in males: 47. Foreign factors affecting reproduction in males: 50. Hormonal control of reproduction in females: 50. Endocrine control of the menstrual cycle: 53. Production and release of gastric acid: 56. Hormonal control of the intestinal phase: 57. Cck release and effects on pancreas: 58. Divisions of the autonomic nervous system: the ans has three divisions, sympathetic, parasympathetic. The parasympathetic nervous system: parasympathetic neurons, parasympathetic ganglia lie within or near the organ innervated. Immersion stimulates cutaneous cold receptors (whole body: activation of the sympathetic nervous system, results in tachycardia, result 2 opposing influences acting on the heart simultaneously. Autonomic neurotransmitters: activate target cells, released from varicosities irregular expansions on the axon of a neuron, produce diffuse, non-directional release at the end of a neuron, preganglionic-postganglionic synapse.