PSYC 3P68 Lecture Notes - Lecture 2: Raphe Nuclei, Deconstruction, The Technique
Document Summary
Transection: removing or disconnecting regions of the brain. Cerveau isole = sleeping brain transect brainstem at midbrain. Encephale isole = normal brain separate brain from spinal chord. Therefore, something b/w midbrain and spinal chord thought to be important for wakefulness. transect regions of brain to determine localization of function. Moruzzi & magoun: provided general understanding of brain regions involved in s/w states. Alert wake low voltage, mixed frequency wave forms blinking high emg showing bursts of activity. Relaxed wake eyes closed alpha eeg waves 8-12hz steadier eyes. More recent work has localized 2 more specific structures (pb and pc); no other areas are as necessary as these for wakefulness lesions to basal forebrain, produce coma, substantiating this regions role in wakefulness. Lesions to midbrain and basal forebrain lead to decreased cortical arousal. Red w neurons are highly active during wake state; inactive during sw sleep.
