BIOL 1010 Lecture Notes - Lecture 8: Metagenomics, Gene Expression, Allele Frequency

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Lecture 8: human genome project and the omics -wednesday, november 3, 2010. Omics: a whole bunch of techniques that split out of genome project. Nutrigenomics (how body reacts to food you eat) *we"ve already discussed first three, will get to last three. Symbol on left- simple for genome project- communication between people in biology, chemistry, physics, informatics (sequencing dna) 3% of budget devoted to ethics (philosophers, sociologists study ramifications) Shown us we"re at the beginning of dealing with this. 2003: scientists involved in hgp achieved goal- sequence of about 3 million bp. Dna sequence- genetic constructions for building human. We"re in the post-genomic area (after sequencing genome) Has changed the way we do basic and applied medicine (agriculture, medicine) Humans are 99. 9% identical: 3 billion bases in haploid genome, comes out to approximately 3 million nucleotide differences between humans, 0. 1% is actually sizeable number of differences. Only about 2% codes for proteins- differences between individuals are pretty small.

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