BIOL 2104 Lecture Notes - Lecture 4: Heterogametic Sex, Sister Chromatids, Synaptonemal Complex

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Lectures 4 and 5: chromosomal basis of inheritance i and ii. Features of a chromosome (homologous vs. non-homologous chromosomes, sister chromatids, centromere, etc) Structure of human x and y chromosomes, along with process of sex determination in humans. Mechanisms of sex determination in species other than humans (e. g. drosophila and birds) Phases of cell cycle and stages of mitosis (p2mat) Stages of meiosis, including process of synapsis (recombination). You do not need to memorize the names of stages within prophase i (leptotene, etc) Be able to determine the number of chromosomes, centromeres, chromatids, tetrads, and/or dyads at various stages of mitosis and meiosis. Know the differences between mitosis and meiosis (table 4. 3 in hartwell et al. ) Know how meiosis generates genetic diversity and provides a physical basis for mendel"s laws. Be able to determine outcomes (both phenotypes and genotypes) of crosses involving x-linked genes and be able to work backwards from progeny to parent.

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