HLTH 1001 Lecture 5: HLTH 1001 Lecture Notes 5
7 Feb 2017
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Document Summary
Cellular and molecular origins of health and disease. Disease is associated with dysfunction in the smallest units of life. Disease is associated with genetic mutation, altered mrna and altered protein production. Long polymer made of repeating units called nucleotides. Composed of 2 helical chains bound by hydrogen bonds. Structure is dynamic along its length, making it capable of coiling into tight loops. Genomic dna is tightly packed by the process called dna condensation. Human haploid genome is 3 billion base pairs- most are diploid. Human genome has 20 000 to 25 000 protein coding genes. Humans have 23 chromosomes that localize to chromosome territories in the nucleus. Described by gregor mendel"s experiments with pea plants. Defined by gene location and phenotype is dominant or recessive. Alteration in the number or structure of chromosomes. Genomics: the study of genes and their functions. April 2003 hgp is completed and released.
