NEUR 1203 Lecture Notes - Lecture 6: Vertebral Artery, Blood Vessel, Hypercholesterolemia
Document Summary
Stroke: stroke, 2nd leading cause of death globally, has been for 15 years. In the u. s. , approximately 800,000 people suffer a stroke each year. Ischemia lack of blood flow to tissue or organ: stroke interruption of blood flow to the brain, two types of disrupted blood flow: Ischemic: blockage in blood vessel (80% of strokes: hemmorhagic: rupture in blood vessel (20% of strokes, these tend to be a lot more serious . Involves bleeding in the subarachnoid space: most often, caused by a burst aneurysm, aneurysm: blood-filled bulge in weakened blood vessel wall, mortality rate: 40-50% (i. e. prognosis not good) Lack of blood flow hypoxia (lack of o2: brain can adapt to this (at least partially, might be that tia primes (preps) brain to deal with upcoming larger event. Lactic acid build up: more acid = more membrane _permiability_, because of this is cannot maintain its resting potneital and eventually dies off, the cells swell, and boom!