NEUR 3200 Lecture Notes - Lecture 10: Bioavailability, Pharmacokinetics, Drug Interaction
Document Summary
May 2nd, 2017: pharmacology is the study of drug action, interactions that occur between a living organism and chemicals that alter normal biological functions. Mechanisms and resulting behaviors: parkinson"s disease and l-dopa, the term drug has many meanings: A chemical that is likely to be abused: an exogenous chemical that significantly alters the function of certain bodily cells when taken into the body (chemical is generally not required for normal function) External to the body, likely to be abused, and has psychoactive effect. Food and other substances derived from plants and other natural sources can elicit potent drugs effects. Natural vs. synthetic: physical and biochemical interactions of drug with target site. Specific (binding) or non-specific (response) non-specific drug interaction could lead to the individual being hyperactive: based on unique characteristics of the individual. Genetics, metabolism: pharmacokinetics is the study of drug absorption, distribution within the body, and drug elimination. Drug absorption: depends on the route of administration.