NEUR 3403 Lecture Notes - Lecture 4: Cardiac Output, Internal Control, Adipose Tissue
4 Sep 2016
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Document Summary
Prenatal and early postnatal events influence the corticosterone response. What does cort do? cortisol/corticosterone -> response to stressor. Hypertension: increased fluid in bloodstream, increased hypertension (treatment - diuretics) Chronic stress: cortisol/ corticosterone response can diminish with repeated stressors. Decrease in cortisol release (doesn"t mean decrease in feeling stressed) Adaptation to repeated stress is not necessarily indicative of reduced anxiety. Injection of steroid decreases hpa axis activity (with depression, won"t have reduction of cortisol) Morning response: cortisol levels have a circadian rhythm increases in the morning, decreases throughout the day, increases throughout the night. If you"re not a morning person, cortisol levels high later in the day and effect ability to go to sleep social jetlag circadian rhythms and cortisol not in sync) Oxytocin will cause development of maternal behaviour in virgin female rats. Effect of acute stress, chronic homotypic stress, and chronic heterotypic stress on corticotropin-releasing factor (crf; a) and oxytocin (oxt; b) mrna expression in the paraventricular nucleus (pvn).
