CHEM 271 Lecture Notes - Lecture 13: Cytidine Triphosphate, Guanosine Triphosphate, Oxidative Phosphorylation
13 Dec 2016
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Document Summary
You should know what a metabolic pathway is, what catabolic and anabolic pathways are, how coupled reactions can be used to drive a reaction. Metabolism is essentially a linked series of chemical reactions that begins with a particular molecule and converts it into some other molecule or molecules in a carefully defined fashion. Some reactions can be either anabolic or catabolic depending on the energy conditions of the cell (amphibolic pathways) Biosynthetic and degreadative pathways are almost always distinct (one direction) to prevent futile cycling. A pathway must satisfy two criteria: 1) individual reactions must be specific: entire set of reactions in the pathway must be thermodynamically favored. The overall free energy change for a chemically coupled series of reactions is equal to the sum of the free energy changes of the individual steps. A thermodynamically unfavoured reaction can be driven by a thermodynamically favorable reaction to which it is coupled.
