PHYL 2041 Lecture Notes - Lecture 2: Tetrodotoxin, Nernst Equation, Weighted Arithmetic Mean
19 Sep 2018
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Phyl 2041 lecture 2 september 6, 2018 electrical properties of cells: membrane potential. In comparison with the extracellular fluid, the intracellular fluid is characterized by a low [na+] and a high [k+]. The na- glucose and na-amino acids symporters use the energy in the na electrochemical gradient, directed to na into the cell, to drive the secondary active cellular uptake of glucose and amino acids. The membrane voltage drives cl out of the cell through cl selective channels, thus lowering the intracellular concentration below that of the extracellular fluid. Some ion channels would always be opened due to leak conductance even without electrical charge. The driving force determines how much net ion flows into the membrane. Conductance is the ability for an conductor (ion channels) to conduct charges (electrons). The larger the channel pores for the channels, the large the charge. Figure 2. 3 p. 23 cell model depicting how cellular.
