PSYO 1011 Lecture Notes - Lecture 4: Eric Kandel, Spaced Repetition, Neurogenesis
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Hebb"s law: neurons that re together wire together if one neuron activates another neuron enough then it connects the two (or more) neurons stronger, use it or lose it practice strengthens memory. Possible mechanisms: neurogenesis, dendrite growth more dendrite = more connections without having to have more neurons, long term potentiation (ltp) Long term potentiation (ltp: strengthening of synaptic connection when one neuron repeatedly excites another. Instead we increase number of neurons: increasing the number of dendrites, can cause more connections without having to have more neurons, this will also strengthen memory, looked at a simpler model, looked at the sea slug. What happens to make them potentiate to have a memory be stored based off how the neurons talk to each other. When you block creb you block the memory. Tuesday, november 24, 2015: creb promotes growth of new synapses (looking to increase memory by increasing creb)