BIOL-2126EL Lecture Notes - Lecture 15: Nuclear Pore, Protein Targeting, Nuclear Membrane

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16 Dec 2015

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Membrane-enclosed organelles evolved in different ways: organelle membranes likely came from the folding inwards of plasma membrane, endomembrane system, organelle interiors communicate by budding vesicles that fuse with one another, interiors are treated as extracellular. Sunday, october 18, y: proteins moving into the er, mitochondria/chloroplasts move across membrane though protein translocaters, proteins unfold to move across membrane, proteins moving from er to endomembranes move through transport vesicles, pinch off from er and fuse with organelles. Signal sequences direct proteins to the correct compartment: signal sequences are often removed from finished protein, signal sequences may change from protein to protein. Proteins enter the endoplasmic reticulum while being synthesized: entry point for proteins destined for other organelles. Start and stop signals determine the arrangement of a transmembrane protein in the. Vesicular transport: budding and fusion of transport vesicles. 5: proteins are modified more in the golgi.

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i need help with this homwork please choose the correct answers and just be claer to read and understand for the slect the apply qusestions too and it is important i realy need the right answers so please be claer not write randomly i really need the correct answers to study for my test so hop you can help me

Question 1

What is the smallest cell you could find?

Question 2

TEMs appear as 3D images

True

False

Question 3

Bacteria are what cell type? Write one word as the answer in lowercase and using no syntax.

Flag this Question

Question 42 pts

ALL eukaryotic cells have which of the following. Click all that apply.

membrane enclosed cell organelles

mitochondria

Question 5

Prokaryotes and eukaryotes both have which if the following cellular components. Click all that apply.

Question 6

I am made of one 60s and one 40s subunit, which organelle am I?

protein

lipid

bacterial ribosome

Question 9

The difference between the rough and smooth ER is

the rough produces lipids where as the smooth does not

the rough has many folds and convolutions where as the smooth does not

the rough has ribosome embedded and the smooth does not

the rough is closer to the cell membrane whereas the smooth is closer to the nucleus

Question 10

The site where many lipids, including cell membrane is produced.

Question 11

Name the organelle: In muscle cells in particular, I would increase in number and size in response to frequent exercise

Question 12

In animal cells, glucose would be mobilized from its storage molecule (glycogen) in this part of the cell.

Question 13

Which of these is associated with the rough ER

production of carbohydrates

production of steroid hormones

production of ATP

production of proteins that are secreted from the cell

Question 14

Which organelle sorts, modifies and stores substances produced on the rough ER. Write two words as the answer in lower case separated by a space.

Question 15

Which organelle is responsible for ATP production. Write one word in the singular as the answer.

Question 16

You inherit all of your mitochondria from your

father

half from your mother and half from your father

your siblings

mother

Question 17

An organelle that contains chlorophyll

Question 18

Microtubules have a variety of roles, which of the options below is NOT one of them?

separate chromosomes

cilia and flagellum movement

tracks for organelle movement

constrict the cell during cell division

Question 19

Made of tubulin subunits

microfilaments

chromosomes

intermediate filaments

microtubules

Question 20

Name the part of the cytoskeleton that is made of two twisted rods of actin. Write one word as the answer in lower case.

Question 21

Which part of the cytoskeleton is made of the same protein as your hair and nails?

microfilaments

microtubules

Intermediate filaments

Question 22

The extracellular matrix is found outside of, but attached to the cell membrane?

True

False

Question 23

Which of the options below is an important function of the extra cellular matrix?

connecting cells together

regulate the movement of substances into and out of the cell

helping cells divide into two cells

keeping the cell in a fixed and ridged shape

Question 24

Which part of the cell wall has a high pectin content?

Question 25

Plants have mitochondria, chloroplasts, a cell wall, and nuclei.

True

False

Question 27

What accounts for 40% of the protein in our bodies?

Question 28

Animal cells have cell walls

True

false

QUESTION 30

The function of centrosome is:

	1.	Microtubule initiation and organization in animal cells
	2.	Organization of thin filaments
	3.	Depolymerization of microtubules
	4.	Organization of intermediate filaments

2.5 points

QUESTION 31

The destinations of proteins synthesized on "free" ribomsomes include:

	1.	Endoplasmic reticulum
	2.	Nucleus
	3.	Mitochondria
	4.	Lysosomes

2.5 points

QUESTION 32

Microtubules can be assembled and disassembled quickly in response to the cellular changes is because:

	1.	Cells synthesize tubulin proteins very fast.
	2.	Cells can turn other cytoskeletal filaments into microtubules
	3.	Microtubules have an instable plus end and microtubules are probably organized by weak non-covalent interactions
	4.	The motor proteins of microtubules can organize the microtubules in response to the cellular changes

2.5 points

QUESTION 33

Both signal recognition particle and a translocon in rough endoplasmic reticulum membrane can recognize and bind to the signal sequence of a secretory protein, so they play the exact same role during protein co-translational translocation.

True

False

2.5 points

QUESTION 34

Rough endoplasmic reticulum is so named is because:

	1.	It has many proteins associated with its surface.
	2.	It has ribosomes associated with its cytosolic surface.
	3.	It is associated with nuclear membrane.
	4.	It has vesicles budding off its surface.

2.5 points

QUESTION 35

The membrane vesicles that transport materials between membrane compartments have a protein coat. The protein coat has similar functions in different vesicles. These functions include:

	1.	Help the enclosed material fold correctly.
	2.	Help degrade the protein in the vesicles
	3.	Maintain the internal pH of the vesicles
	4.	Function as mechanical device to form a vesicle and select the components to be carried by a vesicle.

2.5 points

QUESTION 36

Lysosomes are important for:

	1.	Receptor-mediated endocytosis.
	2.	Breaking down foreign particles brought into the cells by endosomes
	3.	Regulating the process of organelle turnover.
	4.	Protein trafficking between membrane compartments

2.5 points

QUESTION 37

Which of the following is correct about membrane biosynthesis?

	1.	Membranes are synthesized in Golgi Complex.
	2.	Membranes arise from preexisting endoplasmic reticulum membranes.
	3.	Membranes are synthesized on ribosomes.
	4.	Membranes of all organelles have the same composition of proteins and lipids, since they all originate from endoplasmic reticulum.

2.5 points

QUESTION 38

During skeletal muscle contractions, the shortening of the muscle fibers is because of:

		The shortening of the thin and thick myofilaments.
		The shortening of the cytoskeletal filaments.
		The kinesin proteins moving over microtubules.
		The actin and myosin filaments sliding over each other.

2.5 points

QUESTION 39

The assembly and disassembly of microtubules is regulated by rate of growth and shrinkage of the plus end.

True

False

2.5 points

QUESTION 40

The functions of Golgi complex include:

	1.	O-linked oligosaccharides and most of a cellâs complex polysaccharides are assembled in Golgi complex
	2.	Cis Golgi complex sorts proteins
	3.	Trans Golgi complex segregates proteins in different types of vesicles for dilevery.
	4.	N-linked oligosaccharides are further processed in Golgi complex

ochrecoyote721

Value: 1

Anabolic pathways of metabolism are pathways that:

a. build complex molecules from simple ones.

b. release stored chemical energy.

c. take place primarily in skeletal muscle

d. make large quantities of ATP.

Value: 2

The sum of all chemical reactions in a cell is referred to as _______________.

Value: 3

Organisms that derive both their energy and carbon from organic compounds are:

a. photoautotrophs.

b. chemoautotrophs.

c. chemoheterotrophs.

d. photoheterotrophs

Value: 4

It is often stated that the phosphate bonds in ATP are "high energy," but in fact, they are not notably high in energy. Rather, they are easy to break, and the âG of hydrolysis is a "useful" quantity of energy. What makes the phosphate bonds easy to break?

a. They are close to the destabilizing nitrogenous base adenosine

b. Positive charges on amino groups repel each other.

c. Negative charges on phosphate groups repel each other

d. High acidity attacks bonds between amino acids.

Value: 5

Which of the following describes ATP hydrolysis? Select all that apply

[mark all correct answers]
a. exergonic

b. spontaneous

c. often coupled to a reaction that has a positive ÎG

Value: 6

Which of the following describes catabolic reactions?

a. They are endergonic and have a negative change in free energy

b. They are exergonic and have a negative change in free energy

c. They are exergonic and have a positive change in free energy.

d. They are endergonic and have a positive change in free energy.

Value: 7

Why are cells not infinitely big?

a. Because they wouldn't fit in an organism

b. Because they would have a small surface area:volume ratio and substances would diffuse in and out too slowly

c. Because they would have a large surface area to volume ratio and substances would diffuse in and out too quickly

Value: 9

How is organelle movement around cells controlled?

a. the nucleus directs the movement of organelles in a cell

b. the cytoskeleton is like a monorail that moves organelles in a cell via motor proteins

c. organelles do not move, they have a fixed position in the cell

d. organelles move by facilitated diffusion in the cell

Value: 10

1. Prokaryotic cells lack:

a. a. A nucleus

b. organelles

c. cell membrane

d. DNA

e. A and B

Value: 11

Rough endoplasmic reticulum (rER)

a. a. Makes cell membranes

b. has ribosomes attached

c. are a site of protein synthesis

d. all of the above

Value: 12

Match the items.

The task is to match the lettered items with the correct numbered items. Appearing below is a list of lettered items. Following that is a list of numbered items. Each numbered item is followed by a drop-down. Select the letter in the drop down that best matches the numbered item with the lettered alternatives.

a. help to digest worn-out or damaged organelles.
b. Takes in molecules in transport vesicles, modifies them, and sends them back out in vesicles
c. makes sugar
d. makes ATP
e. assembles the ribosomes
f. gives the cell structure
g. move material around the cell

1. vesicles	a b c d e f g
2. cytoskeleton	a b c d e f g
3. the golgi apparatus	a b c d e f g
4. lysosomes	a b c d e f g
5. mitochondrion	a b c d e f g
6. chloroplast	a b c d e f g
7. nucleolus

BIOL-2126EL Lecture Notes - Lecture 15: Nuclear Pore, Protein Targeting, Nuclear Membrane

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