BIOL 202 Lecture Notes - Lecture 15: Wild Type, Zygosity, Chromosome
Document Summary
Biol 202 basic genetics-lecture 15 molecular basis of inheritance: chromosomes are physical basis of heredity. When chromosome number is disrupted, the embryo cannot develop normally: evidence in sex linked trait. Morgan observed that some traits (e. g. fruit fly white eye color) can be associated with the presence of x chromosome. Why it is significant: the difference between x and y chromosomes are easy to observe under microscope; a solid evidence for relationship between chromosomes and phenotypes: when chromosome segregate properly, traits also segregate properly, and vice versa. Example of fruit fly crosses with a x linked recessive trait. Mutant inbreed female cross with heterozygous male. Progeny be should be wild type female or mutant male. Back cross exceptional female to wild heterozygous male. Progeny is both mixed 1:1 ratio of wild and mutant type in female and male. The phenomenon is a result of unequal segregation of chromosome.
