ANSC 312 Lecture Notes - Lecture 16: Hemolytic Anemia, Neutrophilia, Hypogammaglobulinemia
15 Apr 2019
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*please note that these notes complement the lecture slides. Autoimmune diseases: the body is not capable to differentiate between self and. Autoimmune haemolytic anemia -> destruction of red blood cells. Systemic lupus erythematous -> dna, histones, erythrocytes, lymphocytes, platelets are targeted by antibodies. Anatomically hidden antigens -> sperm, lenticular proteins, and alpha-casein. Molecular mimicry -> antigen inducing immune response is not the same that reacts with the antibody. Immunodeficiency diseases: the immune system cannot contain the pathogen. It can be due to any defect in the function of the immune cells. Chs: genetic disorder, immunodeficiency, albinism, bleeding, abnormal neutrophils and nk cells, deficiency in phagolysosome formation, cannot kill bacteria very vulnerable to infectious agents. Lad: genetic disorder, neutrophilia, poor wound healing, inflammation, infections. Scid: cannot have a specific immune response, b and t cells cannot bind antigens, Agammaglobulinemia: b cells don"t differentiate properly and do not produce. Can acquire immunodeficiency diseases, caused by virus, toxins or drugs.
