INDS 111 Lecture Notes - Lecture 25: Publication Bias, Pharmaceutical Industry, Monoamine Neurotransmitter
Document Summary
Many hypotheses: serotonin, dopamine, glutamate, meurotrophin, monoamine, neuroendocrine . Prescription issues today: diagnostic exuberance, off-label uses for medications and publication bias. Without clear guidleines for diagnosis- every problem appears as if for the first time- the solution has to be worked out each time. gained. Diagnosis facilitates learning and provides the framework to disseminate the knowledge. Provides the basis for thinking about treatment and management. We have the dsm, first derived in 1952, with six subsequent iterations. "america"s leading psychiatrists weren"t about to renounce the only scriptures they had- mostly because, as much as they knew the dsm was flawed, they didn"t have anything with which to replace it. " But there might not be a need for diagnosis; 72% of patients in the us are willing to take antidepressants without a prescription. When common conditions were studied to improve the definition of diseases, most of the reformulations resulted in more people being diagnosed.