NSCI 300 Lecture Notes - Lecture 4: Human Subject Research, Miasma Theory, Yellow Fever

• School: McGill University
• Department: Neuroscience
• Course: NSCI 300
• Professor: Eric Racine

Document Summary

John hunter and gonorrhea: developed both gonorrhea and syphilis, major walter reed, first experimented on his highly trained medical personnel. Including lazear, who developed yellow fever and died: historically, medical research used to be a small, artisanal enterprise ( science in the basement , changed in the late 1800s-early 1900s, became a large-scale, industrial enterprise. Infrastructural changes (hospital/medical facilities: after world war ii, transformation. Inspired by the funding structure that had been used to develop the atomic bomb, the radar : countries began to recognize the power that could be gained through research, 3rd promoting factor : rise of drug regulations. Speaker : jonathan kimmelman: series of medical scandals (eg children born missing limbs => cf last lecture, public policies driven by scandals. Founding scandals: nazi experiments & subsequent trials, experiments. Respect for persons: capacity to give consent, minimization of risk (non-therapeutic drugs need to be no more than minimal risk when trying on children, 2.