PSYC 211 Lecture Notes - Sublingual Administration, Abdominal Wall, Suppository

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Published on 22 Apr 2013
School
McGill University
Department
Psychology
Course
PSYC 211
1
PSYC 211
How do neurons communicate
with each other?
Dr. Yogita Chudasama
Stewart Biology, Room N8/4
The Synapse
A synapse is a junction between the terminal button of the sending neuron and a portion
of the dendritic membrane of the receiving neuron.
Synaptic transmission is the transmission of messages from one neuron to another
through a synapse
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2
Detail of the Synapse
Presynaptic membrane is
the membrane of the
terminal button (the
sending cell). This is
where neurotransmitter is
released
Postsynaptic membrane is
the membrane of the
receiving cell either on the
soma or the dendrite
Synaptic cleft is the
space between the
pre- and postsynaptic
membranes. It is filled
with an extracellular
fluid.
Synaptic vesicles
contain molecules of
neurotransmitter. They
attach to the
presynaptic membrane
and release
neurotransmitter into
the synaptic cleft
Postsynaptic Potentials (PSP)
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Postsynaptic Potentials (PSP)
Sodium-potassium channels keep Na+ outside the cell.
When sodium channels are opened, the influx of Na+
causes a depolarisation -
Excitatory Postsynaptic Potential (EPSP)
Postsynaptic Potentials (PSP)
If potassium channels open, K+ leave the cell.
Potassium is positively charged. It’s efflux causes a
hyperpolarisation -
Inhibitory Postsynaptic Potential (IPSP)
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