Class Notes (836,136)
Canada (509,645)
Psychology (3,336)
PSYC 211 (269)

Neurological Disorders Lecture Notes

4 Pages
Unlock Document

PSYC 211
Yogita Chudasama

Neurological Disorders – 28/03/12 Tumors -uncontrollable growth of cells that has no function. i) Benign – encapsulated – tumor has distinct border b/w tumor and surround. A surgeon can remove it easily. ii) Malignant – infiltrates the surrounding tissue. No distinction. Can give rise to metastasis in which tumor cells go through the vascular system and grow elsewhere. Any tumor in the brain is harmful. Two ways: 1) Occupies space and compresses the tissue or block the flow of CSF. 2) The tumor invades the surrounding tissue as it grows and destroys the cells in it’s path. Glioma (tumors of the glial cells) is the most common and serious type of tumor. also: Astrocytoma (astrocytes) Ependymoma (ependymal cells in the ventricle) Meduloblastoma (cells in roof of fourth ventricle) Oligodendrocytoma Seizure Disorders (Epilepsy) -sudden, excessive activity of cerebral neurons. In the motor region = convulsion. Partial seizures have a definite focus and remain localized. Simple partial seizures involve changes to consciousness. Complex partial seizures lead to loss of consciousness. Diagnosis relies on EEG, epilepsy is associated with bursts of high amplitude EEG spikes which occur during an attack. Simple seizures during sleep ARE NOT sleep disorders and occur during REM Generalized Seizures (Grand Mal) -widespread involving most of the brain. A grand mal seizure is the most severe. Proceeding the seizure there are changes in mood, sudden jerks of muscular activity, an aura (a peculiar sensation of psychological change) like a bad smell, hallucination, bright lights, euphoria. Nature of the aura depends on the starting focus. Tonic –Colonic Phases: Tonic: Beginning – muscles contract, arms outstretch rigidly, involuntary cry, rigid posture for 15 seconds Colonic: End – muscles tremble, jerk convulsively, eyes roll, face is contorted, sweating and salivation, after 30 seconds breathing begins again and muscles relax. Exhausted sleep. Cause some level of brain damage due to muffled respiration. Petit Mal (absence seizure) -in children: Vacant look, blinking repeatedly, unresponsive. Can occur up to 100 times a day. They can be disruptive to normal activities. Often go undiagnosed. Usually halt in adolescence. Bilateral symmetry according to a 3 second cycle. Causes of Siezures: Scaring of tissue caused by stroke, injury, growing tumor. Alcohol or barbiturate withdrawl. Consequences: -Almost half of seizure patients will have hippocampus damage. A single episode of status epilepticus (during which the patient experiences a series of seizures without regaining consciousness) causes excessive gluatamate release during. Thus, NMDA receptors are involved because: 1) NMDA receptors control calcium channels. Alchohol blocks NMDA. Long term suppression of NMDA receptors (abuse of alch) causes supersenstivity (up-regulation) When an alchoholic suddenly stops drinking, the receptor rebounds. Which causes seizures. Cerebrovascular disorders: Strokes – sudden onset disorder that causes brain damage. Hemorrhagic stroke – bleeding within the brain. Caused when a vessel ruptures due to high blood pressure. Ischemic stroke – caused by a disruption of the blood supply to the brain. Causes: 1) Thrombus – blood clot (air bubble, tumor, fat) 2) Embolus, carried through the blood stream (material) 3) Arteriosclerosis - thickening of the cerebral wall. Stroke Induced release of glutamate kills neurons -K/Na pump channels stop functioning due to the lack of oxygen and glucose. The neuron membrane depolarises which causes excessive glutamate release. -Excessive glutamate triggers influx of Na and Ca ions by way of NMDA receptors. Causes it to propagate to the next cell. Damaged mitochondria produce free radicals. Stroke Treatments: -admini
More Less

Related notes for PSYC 211

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.