BIOLOGY 1M03 Lecture Notes - Lecture 4: Branchial Cleft Cyst, Sebaceous Cyst, Pax6
4 Feb 2018
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Evidence for evolution: extinct species, fossils, ancient dna vestigial traits, transitional forms, evolution in real time, correlation between geography and patterns of diversity (in the past and present) Studying natural selection melanism in moths, antibiotic resistance, darwin"s finches. Genetic basis of selection: candidate gene approaches (darwin"s finches and mice in. Chimps and humans differ by only about 1. 5% of shared nucleotides. If you incorporate insertions and deletions, they differ by about 6% Eyeless and aniridia influence where eyes are located in fruit flies and humans respectively. Presumably both are derived from an ancestral gene with the same function even though the eyes of humans and flies are so different. Ectopic expression of pax6/eyeless in flies cause eyes to grow in weird places. Mutations in homologs of the same gene (pax6/eyeless) cause abnormal development in many diverged species. Similar gill pouch in chick, human and house cat embryos.
