HLTHAGE 1CC3 Lecture Notes - Lecture 4: Twin, Etiology, Antipsychotic

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Schizophrenia, or rather its symptoms, is reportedly found in all cultures across the world: who i(cid:374)(cid:272)ide(cid:374)(cid:272)e: (cid:1005)%, de(cid:271)ata(cid:271)le . O(cid:373)e (cid:272)ultures it"s (cid:374)or(cid:373)al to des(cid:272)ri(cid:271)e aspe(cid:272)ts through ghosts or spirits. Firm notion that there is a disease called schizophrenia, reaffirms the biomedical aspect: men and women equally likely to be diagnosed. Tudies of t(cid:449)i(cid:374)s re(cid:448)eal (cid:272)o(cid:374)(cid:272)orda(cid:374)t rates as high as 5(cid:1004)%, (cid:271)ut if solel(cid:455) ge(cid:374)eti(cid:272) (cid:449)e"d e(cid:454)pe(cid:272)t (cid:272)loser to 100% Twin adoption studies: roughly 7-15% of those children who had mothers hospitalized for schizophrenia also developed it. Figures for average risk for developing schizophrenia: general population: 1, spouses of people with schizophrenia: 2, children of one parent with schizophrenia: 7-15, offspring of two parents with schizophrenia: 27-46, monozygotic(identical) twins: 48-50% Some combinations of genes suspected but research is unclear, inconsistent. High genetic overlap between schizophrenia and bipolar disorder. Viral infections prevalence of winter births. Neuropathology certain sections of the brain suspected.

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