HTHSCI 1DT3 Lecture Notes - Lecture 13: Decarboxylation, Vasoactivity, Blood Test
13 Aug 2020
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Mod. 3-18 non-allergic mechanisms of allergy 1. Ige mediated allergy: time from exposure to symptoms is usually rapid (minutes, small amounts of allergen > large reactions, recurs with re-exposure. Ige can demonstrate by skin prick test, radioallergosorbent test (blood test for allergen specific ige) or elisa. Ige mediated food allergy: skin urticaria (skin rash on upper dermis), angioedema, eczema, gi vomiting, cramps, diarrhoea, respiratory wheeze, stridor, nasal sinusitis (inflammation of sinuses) Cvs hypotension and collapse: may look like ige mediated food allergy, but isn"t, chronic urticaria/angioedema could be autoimmune, cholinergic, genetic or idiopathic. Irritable bowel syndrome: chronic failure syndrome, non-immunological food intolerance, pharmacological (caffeine, nitrites, metabolic (lactase deficiency milk intolerance) Case studies: 50 years old lady, a professional musician, condition: Have episodic facial swelling for 3 months on the right upper cheeks that starts in the early morning while still in bed and last between 2 and 3 days.
