HTHSCI 1H06 Lecture Notes - Lecture 5: Carotid Sinus, Cardiopulmonary Resuscitation, Adrenal Medulla

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Discuss the homeostatic mechanisms employed in response to shock. Discuss examples of shock in each class using a case-study approach. Shock occurs when the cardiovascular system fails to adequately perfuse cells, tissues, Although shock is classified into different types (cardiogenic, hypovolemic, obstructive and organs, resulting in a widespread impairment function. Of cellular metabolism and distributive), all types of shock are characterized by decreased oxygen delivery and/or increased tissue demand for oxygen. Increased work of organs (heart & lungs) 36 atp per glucose vs 2 atp per glucose. Delivery will result in a shift from aerobic respiration to anaerobic respiration. The result is that atp is used more quickly than it is replenished. Body responses to shock utilization. (lactic acid) levels. designed to improve tissue perfusion and oxygen delivery. Initial stage of shock: cellular alterations as a result of decrease oxygen delivery & Compensatory stage of shock: includes neural, hormonal and chemical responses. Progressive stage of shock: equivalent to multi-organ failure.

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