HTHSCI 1LL3 Lecture Notes - Lecture 10: Ribosomal Rna, Guanosine, Cytosol
10 Apr 2018
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Document Summary
Rna synthesis from dna template is called transcription . Rna polymerase- synthesizes in the 5" to 3" direction (reads 3" to 5"), does not need a primer to begin synthesis, and does not have any proofreading capabilities. Eukaryotes have individual rna polymerases for mrna, trna and rrna. Both rrna and trna are only transcribed, not translated, they are helpers in the process of translation. Needed by rna polymerase to recognize where to begin transcription. Consist of an at rich region (tata box) Cis acting since they are located on the same molecule (cis= close to gene) Trans acting molecules enhance or prevent transition (trans= further from gene) Bacterial cells may have a number of genes that are all under the control of one promoter. An operon produced a polycistronic (multiple transcription) that is translated to several proteins. A cap is added to the 5" end of the eukaryotic transcript. It"s guanosine that is methylated by sam (generated by b12)
