HTHSCI 2H03 Lecture Notes - Lecture 4: Weight Loss, Anxiety, Anterior Pituitary
10 Apr 2018
School
Department
Course
Professor
Document Summary
T4 and t3 are derived from the amino acid tyrosine and the element iodine. Clinical considerations: individuals who are iodine insufficient will be unable to produce is seen clinically with the presentation of thyroid hypertrophy and the development of a goiter. In the due to the fact that salt is now iodized: increased levels of t4 and t3 negatively feedback to the hypothalamus and anterior pituitary to turn off secretion of. Normal effect: thyroid hormones regulate the basal metabolic rate, temperature, help to maintain blood pre development. Binds to intracellular receptors (is lipid soluble). Note: t3 is ten times more potent than t4, however, the thyroid predominately produces t converted to t3 by enzymatic cleavage. T3 then enters the cells and binds to intracellular receptors wi. Menopausal women are more likely to have thyroid disorders. It is important to disti menopause and those caused by a thyroid condition.
